In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine.Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Reference of 1120-90-7.
Wong, Marie L. J.;Sterling, Alistair J.;Mousseau, James J.;Duarte, Fernanda;Anderson, Edward A. research published 《 Direct catalytic asymmetric synthesis of α-chiral bicyclo[1.1.1]pentanes》, the research content is summarized as follows. An approach to synthesize α-chiral bicyclo[1.1.1]pentanes I (R = Me, Bn, thiophen-2-yl, etc.) (BCPs) involving the direct, asym. addition of simple aldehydes RCH2CHO to [1.1.1]propellane, the predominant BCP precursor was described. This is achieved by combining a photocatalyst and an organocatalyst to generate a chiral α-iminyl radical cation intermediate, which installs a stereocenter simultaneously with ring-opening of [1.1.1]propellane. The reaction proceeds under mild conditions, displays broad scope, and provides an array of α-chiral BCPs I in high yield and enantioselectivity. They also present a theor. model for stereoinduction in this mode of photoredox organocatalysis.
1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.
3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.
3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., Reference of 1120-90-7
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com