In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. Reference of 5029-67-4.
Okitsu, Takashi;Iwatsuka, Kinya;Nakagawa, Kimie;Okano, Toshio;Wada, Akimori research published 《 Concise preparation and biological evaluations of 9-cis-retinoic acid analogues having an aromatic ring》, the research content is summarized as follows. A series of 9-cis-retinoic acid analogs I (R = Ph, pyridin-2-yl, pyrazin-2-yl, etc.) having an aromatic ring were prepared in only two steps, and were evaluated for transcriptional activities with retinoic acid response element (RARE) and retinoid X response element (RXRE). Among them, compound I ( = 2-naphthyl) exhibited the highest transcriptional activity with RXR selectivity.
Reference of 5029-67-4, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., 5029-67-4.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com