In 2022,Yu, Shilin; Ward, Jas S. published an article in Dalton Transactions. The title of the article was 《Ligand exchange among iodine(I) complexes》.Application In Synthesis of 4-Iodopyridine The author mentioned the following in the article:
A detailed investigation of ligand exchange between iodine(I) ions in [N···I···N]+ halogen-bonded complexes is presented. Ligand exchange reactions were conducted to successfully confirm whether iodine(I) complex formation, via the classical [N···Ag···N]+ to [N···I···N]+ cation exchange reaction from their analogous Ag+ complexes, could be determined solely by using 1H NMR spectroscopy. In instances where the formation of the iodine(I) complex was unclear or in low yield by the traditional cation exchange reaction, a ligand exchange reaction was used to form the desired iodine(I) complexes in a quant. manner. Mixing two homoleptic [N···I···N]+ iodine(I) complexes in 1:1 ratio was found to undergo a statistical ligand exchange, with 1H NMR studies showing that the preferred formation of the relative heteroleptic [N1···I···N2]+ complexes increases with greater differences in the Lewis basicities of two XB acceptors of the complexes involved. The experimental part of the paper was very detailed, including the reaction process of 4-Iodopyridine(cas: 15854-87-2Application In Synthesis of 4-Iodopyridine)
4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Application In Synthesis of 4-Iodopyridine
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com