The author of 《Design and synthesis of a novel banana-shaped functional molecule via double cross-coupling》 were Yang, Bingchuan; Shen, Guodong; Huang, Xianqiang; Liu, Rutao. And the article was published in Molecules in 2019. Safety of 4-Iodobenzoic acid The author mentioned the following in the article:
A novel banana-shaped mol. using 2,8-dimethyl-6H,12H-5,11-methanodibenzo[b,f][1,5]diazocine (Troger’s base) as bent-core was synthesized via double carbon-carbon cross-coupling reaction. The double Sonogashira cross-coupling reaction was optimized by using Pd(PPh3)2Cl2 as catalyst, CuI as cocatalyst and diisopropylamine as base in place of triethylamine. The structure of this compound was confirmed by 1H-NMR, 13C-NMR, Fourier transform IR (FT-IR) spectroscopy and mass spectrometry. After reading the article, we found that the author used 4-Iodobenzoic acid(cas: 619-58-9Safety of 4-Iodobenzoic acid)
4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Safety of 4-Iodobenzoic acidHalogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com