Xu, Jia-Cheng; Yin, Yi-Zhuo; Han, Zhi-Yong published their research in Organic Letters in 2021. The article was titled 《Asymmetric Counteranion Directed Catalytic Heck/Tsuji-Trost Annulation of Aryl Iodides and 1,3-Dienes》.COA of Formula: C6H5ClIN The article contains the following contents:
A chiral anion-mediated asym. Heck/Tsuji-Trost reaction of aryl iodides and 1,3-dienes was presented. Chiral indoline derivatives I [R1 = H, 5-OMe, 6-Me, etc.; R2 = Ms, Ts, Ns; R3 = Me, Ph, 2-naphthyl, etc.] could be afforded with remarkably higher yields and enantioselectivities than our previous chiral ligand-based method. Silver carbonate was employed as both base and halide scavenger to ensure fast and recyclable exchange of the catalytic amount of chiral anions. Fast salt metathesis, as well as the acceleration effect of the chiral anion, could both benefit the stereocontrol of the reaction. In the experimental materials used by the author, we found 4-Chloro-2-iodoaniline(cas: 63069-48-7COA of Formula: C6H5ClIN)
4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.COA of Formula: C6H5ClIN
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com