Name: Trimethylsulfoxonium iodideIn 2021 ,《Ni-Catalyzed Intramolecular Reductive 1,2-Dicarbofunctionalization of Alkene: Facile Access to Podophyllum Lignans Core》 was published in Synlett. The article was written by Xiao, Jian; Wang, Ya-Wen; Qiu, Zhong-Ping; Peng, Yu. The article contains the following contents:
The facile access to the tetracyclic skeleton of podophyllotoxin (5R,5aS,6R,8aR)/(5R,5aS,6S,8aS)-I, a medicinally important lignan natural product, was efficiently achieved via a unique intramol. alkylarylation of the tethered alkene II in dihalide under mild conditions using reductive nickel catalysis. In the experiment, the researchers used Trimethylsulfoxonium iodide(cas: 1774-47-6Name: Trimethylsulfoxonium iodide)
Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Name: Trimethylsulfoxonium iodide
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com