In 2022,Wang, Chang-Sheng; Tan, Ploypailin Siew Ling; Ding, Wei; Ito, Shingo; Yoshikai, Naohiko published an article in Organic Letters. The title of the article was 《Regio- and Stereoselective Synthesis of Enol Carboxylate, Phosphate, and Sulfonate Esters via Iodo(III)functionalization of Alkynes》.Recommanded Product: 88-67-5 The author mentioned the following in the article:
Synthesis of β-Iodo(III)enol carboxylates, I (R1 = Et, Me, Bu, t-Bu; R2 = Et, Ph, thiophen-2-yl, etc.; R3 = 4-oxopentanoyl, benzoyl, 2,2-dimethylpropyl, etc.) phosphates, I (R3 = diethoxyphosphoroso, diphenoxyphosphoroso, dimethoxyphosphoroso, diphenylphosphoroso) and tosylates I (R3 = Ts) can be efficiently performed through regio- and stereoselective iodo(III)functionalization of alkynes R1CCR2. The combination of 1,2-benziodoxole, 1-chloro-1,3-dihydro-3,3-bis(trifluoromethyl)- and silver salt has proven to generate a versatile cationic iodine(III) electrophile to activate alkynes and engage various carboxylic acids R4COOH (R4 = Me, Ph, 2-phenylethenyl, etc.), tri-Et phosphate and p-toluenesulfonic acid as nucleophiles. The β-iodo(III)enol esters serve as starting materials for the synthesis of multisubstituted alkenes I through sequential cross-coupling of the C-I(III) and C-O bonds. In the experimental materials used by the author, we found 2-Iodobenzoic acid(cas: 88-67-5Recommanded Product: 88-67-5)
2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.Recommanded Product: 88-67-5
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com