The author of 《Accelerating Effect of DMAP on CuI Catalyzed Buchwald-Hartwig C-N Coupling: Mechanistic Insight to the Reaction Pathway》 were Roy, Subhasish; Dutta, Mintu Maan; Sarma, Manas Jyoti; Phukan, Prodeep. And the article was published in ChemistrySelect in 2019. Quality Control of 1-Bromo-4-iodobenzene The author mentioned the following in the article:
An efficient methodol. was developed for C-N cross-coupling reaction between aryl halides and amines using a catalytic system comprised of CuI and N,N-dimethylaminopyridine (DMAP). Coupling reactions were carried out in DMSO at 120°C in the presence of 5 mol% CuI, 20 mol% DMAP and 2.5 equiv of KOH. Addition of DMAP was found to be beneficial in significantly accelerating the reaction rate. Both aryl iodides and aryl bromides were successfully coupled with different primary and secondary amines to furnish the desired cross-coupling product in high yield. A copper complex [Cu(DMAP)4I]I, made by combining CuI and DMAP, was found to produce superior results for the Buchwlad-Hartwig cross-coupling reaction. The use of 2 mol% of the copper complex was sufficient to produce high yields of product. In the part of experimental materials, we found many familiar compounds, such as 1-Bromo-4-iodobenzene(cas: 589-87-7Quality Control of 1-Bromo-4-iodobenzene)
1-Bromo-4-iodobenzene(cas: 589-87-7) has been employed as reagent for in situ desilylation and coupling of silylated alkynes, as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids), as substrate in copper-free Sonogashira coupling in aqueous acetone in synthesis of β,β,dibromostyrenesQuality Control of 1-Bromo-4-iodobenzene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com