《CuBr-Catalyzed One-Pot Three-Component Synthesis of Novel 2-(Carbazolyl)benzothiazoles》 was published in Synlett in 2020. These research results belong to Meesala, Ramu; Lee, Yean Kee; Arshad, Ahmad Saifuddin Mohamad; Abdullah, Iskandar; Mordi, Mohd Nizam; Abd Rahman, Noorsaadah. Product Details of 63069-48-7 The article mentions the following:
A facile synthesis of various 2-(carbazolyl)benzothiazoles were synthesized by one-pot CuBr-catalyzed three-component reactions of 2-iodoanilines, aryl aldehydes and elemental sulfur. Reaction exhibited a good functional group tolerance to produce the corresponding 2-(carbazolyl)benzothiazoles in good yields in the absence of any additive. In the experiment, the researchers used many compounds, for example, 4-Chloro-2-iodoaniline(cas: 63069-48-7Product Details of 63069-48-7)
4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Halogenation, in which one or more hydrogen atoms of an amine is replaced by a halogen atom, occurs with chlorine, bromine, and iodine, as well as with some other reagents, notably hypochlorous acid (HClO). With primary amines the reaction proceeds in two stages, producing N-chloro- and N,N-dichloro-amines, RNHCl and RNCl2, respectively. With tertiary amines, an alkyl group may be displaced by a halogen.Product Details of 63069-48-7
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com