Application of 189518-78-3On May 20, 2021 ,《Synthesis of Tetracyclic Indolines through Palladium-Catalyzed Asymmetric Dearomative reaction of Aryl Iodides》 appeared in ChemistrySelect. The author of the article were Li, Yuanfeng; Yue-Su, M. Sc.; Zhang, Hong-Yu; Zhang, Yuecheng; Dong-Han, M. Sc.; Han, Ya-Ping; Zhao, Jiquan; Liang, Yong-Min. The article conveys some information:
A palladium-catalyzed asym. intramol. Heck reaction of aryl iodides with alkynyl carboxylic acids has been developed, delivering various indoline frameworks in moderate to excellent yields (up to 95%) with excellent enantioselectivities (up to 96% ee) and diastereoselectivities (>20 : 1) using BINOL-based phosphoramidite as chiral ligand. This cascade annulation protocol, which tolerates a broad variety of functional groups and is conducted under an argon atm., provides efficient and atom-economical access to structurally diverse 2,3-disubstituted indolines bearing vicinal tertiary and quaternary stereocenters. Addnl., the synthetic products could be converted to useful unique indoline derivatives without loss of enantiomeric excess. After reading the article, we found that the author used (R)-3,3′-Diiodo-2,2′-bis(methoxymethoxy)-1,1′-binaphthalene(cas: 189518-78-3Application of 189518-78-3)
(R)-3,3′-Diiodo-2,2′-bis(methoxymethoxy)-1,1′-binaphthalene(cas: 189518-78-3) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Application of 189518-78-3
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com