In 2022,Leifert, Dirk; Weidlich, Frauke; Adler, Florin; Daniliuc, Constantin G.; Alasmary, Fatmah A.; Studer, Armido published an article in Organic Letters. The title of the article was 《2,3-Difunctionalized Indoles via Radical Acylation or Trifluoromethylation of ortho-Alkynylphenyl Isonitriles》.SDS of cas: 63069-48-7 The author mentioned the following in the article:
A radical cascade to 2,3-disubstituted indoles proceeding via acylation or trifluoromethylation of ortho-alkynylphenyl isonitriles was presented. In these cascades, two C-C bonds and one C-O bond was formed using an inexpensive oxidant and a catalytic copper or iron salt. The starting isonitriles were easily accessible, and com. available aldehydes and fluoromethylation reagents served as reaction partners. Functional group tolerance was high, as documented by the successful preparation of a series of 2,3-disubstituted indoles.4-Chloro-2-iodoaniline(cas: 63069-48-7SDS of cas: 63069-48-7) was used in this study.
4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Amine, any member of a family of nitrogen-containing organic compounds that is derived, either in principle or in practice, from ammonia (NH3). Naturally occurring amines include the alkaloids, which are present in certain plants; the catecholamine neurotransmitters (i.e., dopamine, epinephrine, and norepinephrine); and a local chemical mediator, histamine, that occurs in most animal tissues.SDS of cas: 63069-48-7
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com