Formula: C4H4INO2In 2019 ,《1,2-trans Glycosylation via Neighboring Group Participation of 2-O-Alkoxymethyl Groups: Application to One-Pot Oligosaccharide Synthesis》 was published in Organic Letters. The article was written by Karak, Milandip; Joh, Yohei; Suenaga, Masahiko; Oishi, Tohru; Torikai, Kohei. The article contains the following contents:
The use of 2-O-alkoxymethyl groups as effective stereo-directing substituents for the construction of 1,2-trans glycosidic linkages is reported. The observed stereoselectivity arises from the intramol. formation of a five-membered cyclic architecture between the 2-O-alkoxymethyl substituent and the oxocarbenium ion, which provides the expected facial selectivity. Furthermore, the observed stereocontrol and the extremely high reactivity of 2-O-alkoxymethyl-protected donors allowed development of a one-pot sequential glycosylation strategy that should become a powerful tool for the assembly of oligosaccharides. The results came from multiple reactions, including the reaction of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Formula: C4H4INO2)
1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Formula: C4H4INO2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com