Category: iodides-buliding-blocksOn October 1, 2009 ,《Synthesis of 6-substituted imidazo[2,1-b][1,3]thiazoles and 2-substituted imidazo[2,1-b][1,3]benzothiazoles via Pd/Cu-mediated Sonogashira coupling》 was published in Synlett. The article was written by Kamali, Taghi A.; Habibi, Davood; Nasrollahzadeh, Mahmoud. The article contains the following contents:
The reaction of iodobenzenes with 2-amino-3-prop-2-ynyl-1,3-thiazolium bromide and 2-imino-3-prop-2-ynyl-1,3-benzothiazole, catalyzed by Pd/Cu in aqueous solution, leads to the formation of 6-substituted imidazo[2,1-b][1,3]thiazoles and 2-substituted imidazo[2,1-b][1,3]benzothiazoles, resp. The experimental part of the paper was very detailed, including the reaction process of 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Category: iodides-buliding-blocks)
1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Category: iodides-buliding-blocks Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com