Hu, Zhoumi; Fu, Liang; Chen, Pinhong; Cao, Weiguo; Liu, Guosheng published their research in Organic Letters in 2021. The article was titled 《Enantioselective Intermolecular Aminoalkynylation of Styrenes via Copper-Catalyzed Radical Relay》.Quality Control of 1,2-Diiodoethane The article contains the following contents:
A novel copper-catalyzed intermol. aminoalkynylation of alkenes through a radical relay process has been developed in this work, in which N-fluoro-N-alkylsulfonamides (NFASs) are used as nitrogen-centered radical precursors and alkynyltrimethoxysilanes as alkynylating reagents. This method presents an efficient and straightforward approach to various enantioenriched 2-alkynyl-2-arylethylamines in good yields with excellent enantioselectivity, and these products can be readily converted into a series of synthetically useful chiral terminal alkynes, allenes, alkenes, amines, amino acids, and N-heterocycles. Safety: fluorination with F2/N2 should be conducted in well-ventilated fume hood with careful protection. In addition to this study using 1,2-Diiodoethane, there are many other studies that have used 1,2-Diiodoethane(cas: 624-73-7Quality Control of 1,2-Diiodoethane) was used in this study.
1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the SimmonsSmith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Quality Control of 1,2-Diiodoethane
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com