The author of 《The synthesis and some reactions of 3-(2-aminophenyl)-2-iminothiazolidines. Ring closure of N-(2-thiocyanatoethyl)-o-phenylenediamines: thiazolidine vs. 3,1,6-benzothiadiazocine formation》 were Hornyak, G.; Bertha, F.; Zauer, K.; Lempert, K.; Feller, A.; Pjeczka, E.. And the article was published in Tetrahedron in 1990. Electric Literature of C6H3ClINO2 The author mentioned the following in the article:
When treated with strong acids, the N-(2-thiocyanatoethyl)-o-phenylenediamines (I, R1 = H, Me; R2 = H, Et; R3, R5, R6 = H, Cl; R4 = H, Cl, F3C, MeO2C, Br, I, F, MeO) are cyclized exclusively to 3-(2-aminophenyl)-2-iminothiazolidines (II, X = Cl, EtSO3). Some II are highly active antidepressants of low toxicity. In the experiment, the researchers used many compounds, for example, 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Electric Literature of C6H3ClINO2)
1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine.Electric Literature of C6H3ClINO2 In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com