Synthetic Route of C24H20I2O4On March 1, 2019, Handa, Sachin; Jin, Bo; Bora, Pranjal P.; Wang, Ye; Zhang, Xiaohua; Gallou, Fabrice; Reilly, John; Lipshutz, Bruce H. published an article in ACS Catalysis. The article was 《Sonogashira Couplings Catalyzed by Fe Nanoparticles Containing ppm Levels of Reusable Pd, under Mild Aqueous Micellar Conditions》. The article mentions the following:
Nanoparticles derived from FeCl3 containing the ligand XPhos and only 500 ppm Pd effect Sonogashira couplings in water between rt and 45°. The entire aqueous reaction medium can be easily recycled using an “”in-flask”” extraction Several tandem processes in one pot are illustrated, including a sequence involving five steps (10 reactions) in good overall yield. In the part of experimental materials, we found many familiar compounds, such as (R)-3,3′-Diiodo-2,2′-bis(methoxymethoxy)-1,1′-binaphthalene(cas: 189518-78-3Synthetic Route of C24H20I2O4)
(R)-3,3′-Diiodo-2,2′-bis(methoxymethoxy)-1,1′-binaphthalene(cas: 189518-78-3) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Synthetic Route of C24H20I2O4
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com