In 2019,Green Chemistry included an article by Gong, Xinchi; Wu, Jie; Meng, Yunge; Zhang, Yulan; Ye, Long-Wu; Zhu, Chunyin. Product Details of 624-31-7. The article was titled 《Ligand-free palladium catalyzed Ullmann biaryl synthesis: ‘household’ reagents and mild reaction conditions》. The information in the text is summarized as follows:
A palladium catalyzed Ullmann biaryl ArAr1, Ar1Ar1, ArAr, (Ar = 4-CNC6H4, pyridin-2-yl, 3-MeC6H4, etc.; Ar1 = 4-CNC6H4, 4-MeOC6H4) synthesis has been developed using hydrazine hydrate as the reducing reagent at room temperature The combination of Pd(OAc)2 and hydrazine hydrate works smoothly for the coupling of both electron-rich and electron-deficient aryl iodides ArI and Ar1I, as well as 2-iodopyridine, leading to a wide range of biaryls in good to excellent yields. The reaction requires only 1 mol% Pd(OAc)2 and the in situ generated palladium nanoparticles are found to be active catalysts. After reading the article, we found that the author used 1-Iodo-4-methylbenzene(cas: 624-31-7Product Details of 624-31-7)
1-Iodo-4-methylbenzene(cas: 624-31-7) undergoes Suzuki-Miyaura coupling reaction with phenylboronic acid catalyzed by (Ni,Mg)3Si2O5(OH)4 solid-solution nanotubes loaded with palladium.Product Details of 624-31-7
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com