Formula: C6H4ClIIn 2019 ,《Three-Component Aminoselenation of Arynes》 was published in Organic Letters. The article was written by Gaykar, Rahul N.; Guin, Avishek; Bhattacharjee, Subrata; Biju, Akkattu T.. The article contains the following contents:
The three-component coupling of tertiary amines, arynes, and aryl selenium bromide or diaryl diselenide as an electrophilic selenium source allowing the synthesis of 2-selanyl aniline derivatives is reported. This aminoselenation reaction of arynes installs a C-N and C-Se bond under mild conditions, and the products are formed in moderate to good yields. This reaction is compatible with various functional groups, and the preliminary studies on the mechanism of the reaction is also provided. In the experiment, the researchers used 1-Chloro-3-iodobenzene(cas: 625-99-0Formula: C6H4ClI)
1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Formula: C6H4ClI Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com