Quality Control of Trimethylsulfoxonium iodideIn 2020 ,《Ru(II)-catalyzed C6-selective C-H acylmethylation of pyridones using sulfoxonium ylides as carbene precursors》 appeared in RSC Advances. The author of the article were Fu, Yangjie; Wang, Zhaohui; Zhang, Qiyu; Li, Zhiyu; Liu, Hong; Bi, Xiaoling; Wang, Jiang. The article conveys some information:
A method was described using sulfoxonium ylides as carbene precursors to achieve C6-selective acylmethylation of pyridones catalyzed by a ruthenium(II) complex. This approach featured mild reaction conditions, moderate to excellent yields, high step economy and had excellent functional group tolerance with good site selectivity. Besides, gram-scale preparation, synthetic utility and mechanistic studies were conducted. It offered a direct and efficient way to synthesize pyridone derivatives After reading the article, we found that the author used Trimethylsulfoxonium iodide(cas: 1774-47-6Quality Control of Trimethylsulfoxonium iodide)
Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Quality Control of Trimethylsulfoxonium iodide
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com