da Rosa, Rafael; Grand, Lucie; Schenkel, Eloir P.; Sibelle Campos Bernardes, Lilian; Jacolot, Maiwenn; Popowycz, Florence published an article in 2021. The article was titled 《The Use of 5-Hydroxymethylfurfural towards Fine Chemicals: Synthesis and Direct Arylation of 5-HMF-Based Oxazoles》, and you may find the article in Synlett.Recommanded Product: 15854-87-2 The information in the text is summarized as follows:
The synthesis of 5-HMF-based oxazole compounds I [Ar = 4-MeC6H4, 3-FC6H4, 3-thienyl, etc.] were reported. While 5-HMF could be easily converted into the oxazole derivative through the Van Leusen reaction, the direct arylation step needed to access the final compounds was problematic at first. After optimization, a palladium-catalyzed procedure had been developed and used for the synthesis of a series of 33 derivatives This article reported an extension of the late-stage CH arylation reaction as an application to the oxazole platform derived from biosourced 5-HMF. The challenges in the preparation of the derivatives containing some electron-withdrawing substituents were overcome by the use of a palladium-free method. The results came from multiple reactions, including the reaction of 4-Iodopyridine(cas: 15854-87-2Recommanded Product: 15854-87-2)
4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Recommanded Product: 15854-87-2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com