Computed Properties of C10H7IIn 2022 ,《Cobalt-catalyzed carbonylative synthesis of free (NH)-tetrahydro-β-carbolinones from tryptamine derivatives》 was published in Organic Chemistry Frontiers. The article was written by Zhu, Yiwen; Guo, Binghu; Gao, Shenkui; Ying, Jun; Wu, Xiao-Feng. The article contains the following contents:
A new cobalt-catalyzed carbonylative synthesis of free (NH)-tetrahydro-βcarbolinones I [R1 = H, 7-Me, 6-MeO, etc.; R2 = H, Me, Bn, etc.] from tryptamine derivatives II was developed. This reaction employs a cobalt(II) salt as the non-noble catalyst with TFBen as the CO source, and a variety of free (NH)-tetrahydro-βcarbolinones I were produced in good yields using a traceless directing group strategy. Furthermore, late-stage modifications of several bioactive mols. (sorbic acid, probenecid and febuxostat) could also be realized. The oxidant, silver salt, could be recycled and reused. In the part of experimental materials, we found many familiar compounds, such as 1-Iodonaphthalene(cas: 90-14-2Computed Properties of C10H7I)
1-Iodonaphthalene(cas: 90-14-2) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Computed Properties of C10H7I
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com