《Ruthenium(II)-catalyzed synthesis of CF3-isoquinolinones via C-H activation/annulation of benzoic acids and CF3-imidoyl sulfoxonium ylides》 was written by Wen, Si; Zhang, Yuqing; Tian, Qingyu; Chen, Yanhui; Cheng, Guolin. Category: iodides-buliding-blocksThis research focused ontrifluoromethyl isoquinolinone preparation; benzoic acid trifluoromethyl sulfoxonium ylide activation annulation ruthenium catalyst. The article conveys some information:
A ruthenium(II)-catalyzed C-H activation/annulation reaction of benzoic acids and CF3-imidoyl sulfoxonium ylides enabled by weak O-coordination was achieved. A series of 3-trifluoromethyl-isoquinolinones I [R = Ph, 2-MeC6H4, CH2CH2Ph, etc.; R1 = 8-Me, 7-F, 6-I, etc.; R2 = F, CF2CF3, CF2CF2CF3] were synthesized in 37-75% yields under redox-neutral reaction conditions. In the experimental materials used by the author, we found 4-Iodobenzoic acid(cas: 619-58-9Category: iodides-buliding-blocks)
4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Category: iodides-buliding-blocksIodo alkanes participate in a variety of organic synthesis reactions, which include the SimmonsSmith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com