COA of Formula: C3H9IOSIn 2020 ,《Imidazol-5-one as an Acceptor in Donor-Acceptor Cyclopropanes: Cycloaddition with Aldehydes》 was published in Organic Letters. The article was written by Mikhaylov, Andrey A.; Kuleshov, Andrei V.; Solyev, Pavel N.; Korlyukov, Alexander A.; Dorovatovskii, Pavel V.; Mineev, Konstantin S.; Baranov, Mikhail S.. The article contains the following contents:
Spiro[imidazol-5-one-4,1′-cyclopropanes] behave as donor-acceptor (D-A) cyclopropanes in a formal cycloaddition reaction with aldehydes. The activation of such type of cyclopropanes is achieved with an equivalent of Bronsted acid. The reaction proceeds in high yields of 51-92% and demonstrates moderate diastereoselectivity at the quaternary stereocenter, which is determined by the electron-donating nature of the aldehyde partner. The ease of separation of stereoisomers allowed the creation of a library of 44 spiroannulated tetrahydrofurans with various substitution patterns. After reading the article, we found that the author used Trimethylsulfoxonium iodide(cas: 1774-47-6COA of Formula: C3H9IOS)
Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.COA of Formula: C3H9IOS
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com