Quality Control of 4-Iodobenzoic acidIn 2021 ,《A Three-Component Ugi-Type Reaction of N-Carbamoyl Imines Enables a Broad Scope Primary α-Amino 1,3,4-Oxadiazole Synthesis》 appeared in Organic Letters. The author of the article were Matheau-Raven, Daniel; Boulter, Elizabeth; Rogova, Tatiana; Dixon, Darren J.. The article conveys some information:
A general synthesis of N-protected primary α-amino 1,3,4-oxadiazoles from N-carbamoyl imines, N-isocyaniminotriphenylphosphorane (NIITP) and carboxylic acids was described. Featuring an isocyanide addition reaction with N-carbamoyl imines, this efficient three-component Ugi-type reaction was found to be broad in scope with respect to imine and carboxylic acid coupling partners. Furthermore, versatility of this method was demonstrated by α-amino 1,2,4-triazole synthesis, late-stage functionalization of seven drug mols. and five divergent derivatizations of a primary α-amino 1,3,4-oxadiazole. The results came from multiple reactions, including the reaction of 4-Iodobenzoic acid(cas: 619-58-9Quality Control of 4-Iodobenzoic acid)
4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Quality Control of 4-Iodobenzoic acid
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com