In 2022,Leushukou, Andrei A.; Krech, Anastasiya V.; Hurski, Alaksiej L. published an article in Organic Letters. The title of the article was 《Visible-Light-Promoted Nickel-Catalyzed Cross-Coupling of Alkyltitanium Alkoxides with Aryl and Alkenyl Halides》.SDS of cas: 15854-87-2 The author mentioned the following in the article:
The reported alkyltitanium alkoxides generated in situ from Grignard reagents and Ti(OiPr)4 undergone a photocatalyst-free nickel-catalyzed cross-coupling with organic halides upon irradation with blue light. Mechanistic studies suggested that the reaction proceeds through radical intermediates formed by photochem. decomposition of the alkyltitanium reagents. Various aryl, heteroaryl, and vinyl halides was efficiently alkylated under the reported conditions, including those containing ester and amide groups. The experimental process involved the reaction of 4-Iodopyridine(cas: 15854-87-2SDS of cas: 15854-87-2)
4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.SDS of cas: 15854-87-2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com