In 2019,Organic Letters included an article by Krishnamurti, Vinayak; Barrett, Colby; Ispizua-Rodriguez, Xanath; Coe, Matthew; Prakash, G. K. Surya. Application of 88-67-5. The article was titled 《Aqueous Base Promoted O-Difluoromethylation of Carboxylic Acids with TMSCF2Br: Bench-Top Access to Difluoromethyl Esters》. The information in the text is summarized as follows:
A method for the O-difluoromethylation of carboxylic acids using com. available TMSCF2Br is disclosed. The devised bench-top reaction system is air-stable and offers mild reaction conditions while using readily available reagents and solvents. The method is applicable to both aliphatic and aromatic carboxylic acids while demonstrating compatibility with a range of commonly encountered functional groups. The difluoromethyl esters of FDA approved drugs and pharmaceutically relevant mols. are also presented, demonstrating the potential for late-stage functionalization. The results came from multiple reactions, including the reaction of 2-Iodobenzoic acid(cas: 88-67-5Application of 88-67-5)
2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides.Application of 88-67-5 The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com