In 2022,Gugkaeva, Zalina T.; Mardiyan, Zorayr Z.; Smolyakov, Alexander F.; Poghosyan, Artavazd S.; Saghyan, Ashot S.; Maleev, Victor I.; Larionov, Vladimir A. published an article in Organic Letters. The title of the article was 《Sequential Heck Cross-Coupling and Hydrothiolation Reactions Taking Place in the Ligand Sphere of a Chiral Dehydroalanine Ni(II) Complex: Asymmetric Route to β-Aryl Substituted Cysteines》.HPLC of Formula: 90-14-2 The author mentioned the following in the article:
A practically useful protocol for the asym. synthesis of artificial β-aryl-substituted cysteine derivatives was developed through sequential Pd(II)-catalyzed Heck cross-coupling with aryl iodides and hydrothiolation reaction with various alkyl thiols in the presence of triethylamine taking place in the ligand sphere of a robust and bench-stable chiral dehydroalanine Ni(II) complex. The subsequent acidic decomposition of the single diastereomeric Ni(II) complexes led to the target enantiopure cysteine derivatives The experimental part of the paper was very detailed, including the reaction process of 1-Iodonaphthalene(cas: 90-14-2HPLC of Formula: 90-14-2)
1-Iodonaphthalene(cas: 90-14-2) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the SimmonsSmith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.HPLC of Formula: 90-14-2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com