Feng, Jianling; Wang, Qiang; Duan, Ruomeng; Li, Huadeng; Zheng, Ke; Wang, Xiaoxia; Xie, Guanqun published an article in 2022. The article was titled 《A facile electrosynthesis of N-acyl benzotriazoles from aldehydes and benzotriazole》, and you may find the article in Tetrahedron Letters.Category: iodides-buliding-blocks The information in the text is summarized as follows:
An electrochem. synthesis of N-acylbenzotriazoles I [R = Ph, 4-ClC6H4, 2-naphthyl, etc.] had been developed under mild conditions with good to excellent yields using aldehydes and benzotriazole as starting materials. In addition, a one-pot reaction of aldehyde, benzotriazole and phenol had been achieved affording phenolic esters II [R1 = Ph, 4-MeC6H4, 4-BrC6H4, etc.] in moderate yields under the combination of electricity-on/off conditions, where N-acyl benzotriazole acted as the benign acylating reagent. It was noteworthy the research provided environmental friendly syntheses in that no superstoichiometric hazardous chem. oxidants were required, corrosive/toxic reagents had been avoided and waste production had significantly been reduced. The key of the electrochem. synthesis involved the oxidation of benzotriazole-aldehyde adduct by phthalimido-N-oxy (PINO), which was generated by N-hydroxyphthalimide (NHPI) as a redox mediator. The experimental part of the paper was very detailed, including the reaction process of 4-Iodobenzaldehyde(cas: 15164-44-0Category: iodides-buliding-blocks)
4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Category: iodides-buliding-blocks
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com