In 2019,Organic Chemistry Frontiers included an article by Cai, Libo; Zhu, Xiaoyi; Chen, Jiayi; Lin, Aijun; Yao, Hequan. Reference of Trimethylsulfoxonium iodide. The article was titled 《Rh(III)-Catalyzed C-H activation/annulation of salicylaldehydes with sulfoxonium ylides for the synthesis of chromones》. The information in the text is summarized as follows:
A rhodium(III)-catalyzed C-H activation/annulation of salicylaldehydes e.g., 2-OHC6H4CHO with sulfoxonium ylides RC(O)CH=S(O)(CH3)CH3 (R = Ph, t-Bu, cyclohexyl, thiophen-2-yl, etc.) has been developed for the formation of 2-substituted chromones e.g., I in good yields with broad functional group tolerance. The utility of this strategy was showcased by the late-stage modification of some biol. active mols. Moreover, structurally diverse 2,3-disubstituted chromones II (R1 = Cl, CF3, diethoxyphosphoroso, etc.) were also constructed by the C3 C-H functionalization reactions.Trimethylsulfoxonium iodide(cas: 1774-47-6Reference of Trimethylsulfoxonium iodide) was used in this study.
Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Reference of Trimethylsulfoxonium iodide
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com