《The invention of radical reactions. Part XVI. Radical decarboxylative bromination and iodination of aromatic acids》 was published in Tetrahedron in 1987. These research results belong to Barton, Derek H. R.; Lacher, Brigitte; Zard, Samir Z.. Category: iodides-buliding-blocks The article mentions the following:
Thiohydroxamic esters of aromatic carboxylic acids undergo clean decarboxylative bromination or iodination on treatment with bromotrichloromethane, iodoform, or diiodomethane in the presence of a radical initiator. E.g., reaction of 1-naphthoyl chloride with the Na salt of N-hydroxypyridine-2-thione and BrCCl3 in o-Cl2C6H4 in the presence of AIBN gave 82% 1-bromonaphthalene. In addition to this study using 1-Chloro-4-iodo-2-nitrobenzene, there are many other studies that have used 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Category: iodides-buliding-blocks) was used in this study.
1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Category: iodides-buliding-blocks
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com