Manisha; Gupta, Shiv Shankar; Dhiman, Ankit Kumar; Sharma, Upendra published an article in 2021. The article was titled 《Rh(III)-Catalyzed Selective C7 Halogenation of Indolines》, and you may find the article in European Journal of Organic Chemistry.Application In Synthesis of 1-Iodopyrrolidine-2,5-dione The information in the text is summarized as follows:
An efficient Rh-catalyzed catalytic method has been developed for selective C7 halogenation of N-pyrimidyl indolines I (R = H, 5-Ph, 6-F, OCH2Ph, etc., R1 = H, 2-EtO2C, 3-Me, 2-Me, R2 = H) with N-halosuccinimides (halo = chloro, bromo, iodo) to produce the corresponding halides I (R2 = Br, Cl, I) in good to excellent yields. The advantages of this strategy include broad substrate scope and excellent regioselectivity for C7 functionalization of the indolines and feasibility at the gram scale level. Various control experiments have been performed to understand the reaction pathway. Applicability of current methodol. has been demonstrated by indole synthesis and post-transformation of the C7 halogenated indolines into different valuable mols. The reaction is also applicable to the preparation of halogenated carbazoles II (R2 = Br, Cl, I) and tetrahydroquinolines III (R2 = Br, I). In the experimental materials used by the author, we found 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Application In Synthesis of 1-Iodopyrrolidine-2,5-dione)
1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Application In Synthesis of 1-Iodopyrrolidine-2,5-dione
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com