《POP-Pd(II) catalyzed easy and safe in situ carbonylation towards the synthesis of α-ketoamides from secondary cyclic amines utilizing CHCl3 as a carbon monoxide surrogate》 was written by Islam, Sk Safikul; Riyajuddin, Sk; Molla, Rostam Ali; Yasmin, Nasima; Ghosh, Kaushik; Islam, Sk. Manirul. Name: 1-Bromo-4-iodobenzene And the article was included in New Journal of Chemistry in 2020. The article conveys some information:
A novel complex catalyst, POP-palladium(II), was synthesized. The developed catalyst was characterized by XRD, EDX, SEM (FE-SEM), HR-TEM, FTIR spectroscopy, UV-vis spectroscopy, TGA and BET isotherm anal. The reactivity of the incorporated palladium(II) catalyst was tested in the in-situ carbonylation of aryl iodides and secondary cyclic amines to the resp. α-ketoamides at 80°C. A large number of aryl iodides combined with CO followed by 2° amines to generate the corresponding α-ketoamides with high selectivity. This Pd(II) complex catalyst exhibited superb catalytic activities and was easily recovered after the reaction by an easy filtration method. The catalyst was reused for up to six consecutive cycles without much loss in its activity. In the experimental materials used by the author, we found 1-Bromo-4-iodobenzene(cas: 589-87-7Name: 1-Bromo-4-iodobenzene)
1-Bromo-4-iodobenzene(cas: 589-87-7) is mainly used as the OLED pharmaceutical intermediate, as reagent for in situ desilylation and coupling of silylated alkynes, as substrate in copper-free Sonogashira coupling in aqueous acetone..Name: 1-Bromo-4-iodobenzene It is also used in synthesis of β,β,dibromostyrenes, as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids)
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com