SDS of cas: 1774-47-6In 2021 ,《Synthesis of Pyrazolo[1,2-a]cinnolines via Rhodium(III)-Catalyzed [4+2] Annulation Reactions of Pyrazolidinones with Sulfoxonium Ylides》 appeared in Advanced Synthesis & Catalysis. The author of the article were Hu, Shulei; Han, Xu; Xie, Xiong; Fang, Feifei; Wang, Yong; Saidahmatov, Abdusaid; Liu, Hong; Wang, Jiang. The article conveys some information:
A method to synthesize pyrazolo[1,2-a]cinnolines via rhodium(III)-catalyzed C-H activation of pyrazolidinones and subsequent [4+2] annulation of sulfoxonium ylides was developed. 5-Substituted or 5,10-disubstituted pyrazolo[1,2-a]cinnolines could be obtained by slightly adjusting the reaction conditions. Gram-scale synthesis and practical transformations proved the practicability of this method. The mechanism of this method was proposed in the article on the basis of preliminary mechanistic results and previous reports. This method features simplified operation, metal-oxidant free, and readily available reactants. In the experiment, the researchers used Trimethylsulfoxonium iodide(cas: 1774-47-6SDS of cas: 1774-47-6)
Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.SDS of cas: 1774-47-6
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com