Recommanded Product: 4-IodopyridineIn 2022 ,《Synthesis and Mechanistic Investigation of Bipyrazolo[1,5-a]pyridines via Palladium-Catalyzed Cross-Dehydrogenative Coupling of Pyrazolo[1,5-a]pyridines》 appeared in Journal of Organic Chemistry. The author of the article were Hsiao, Pu-Yen; Chang, Rong; Sue, Andrew C.-H.; Chu, Jean-Ho; Liao, Guan-Wei; Lee, Yi-Hsin; Huang, Jui-Yang. The article conveys some information:
The synthesis of a range of 3,3′-bipyrazolo[1,5-a]pyridine derivatives via direct cross-dehydrogenative coupling of pyrazolo[1,5-a]pyridine precursors was herein presented. This simple and efficient methodol. involving palladium(II)-catalyzed C-H bond activation showed good functional group tolerance and product yield (up to 94%). Through the mechanistic insights gained from both kinetic isotope effect exptl. studies and d. functional theory calculations, a plausible reaction mechanism was outlined. Furthermore, subsequent derivatizations of the resulting 7,7′-diaryl-3,3′-bipyrazolo[1,5-a]pyridines, executed by performing palladium-mediated ortho C-H bond activation followed by hypervalent iodine-induced chlorination, rendered this series of compounds more extended π-conjugation and twisted conformations. The study on these bipyrazolo[1,5-a]pyridine-based luminogens provided new opportunities for tailor-made organic luminescent materials.4-Iodopyridine(cas: 15854-87-2Recommanded Product: 4-Iodopyridine) was used in this study.
4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.Recommanded Product: 4-Iodopyridine
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com