Bakherad, Mohammad; Keivanloo, Ali; Kalantar, Zahra; Jajarmi, Saeideh published an article on January 12 ,2011. The article was titled 《Pd/C-catalyzed heterocyclization during copper-free Sonogashira coupling: Synthesis of 2-benzylimidazo[1,2-a]pyrimidines in water》, and you may find the article in Tetrahedron Letters.Reference of 1-Chloro-4-iodo-2-nitrobenzene The information in the text is summarized as follows:
An efficient synthesis of 2-benzylimidazo[1,2-a]pyrimidines I (R = 4-O2NC6H4, 3-O2NC6H4, 4-BrC6H4, etc.) in water is accomplished via Pd/C-catalyzed reaction of 2-imino-1-(2-propynyl)pyrimidine with various aryl iodides in the presence of K2CO3 as the base.1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Reference of 1-Chloro-4-iodo-2-nitrobenzene) was used in this study.
1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Reference of 1-Chloro-4-iodo-2-nitrobenzene Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com