In 2022,Wang, Xi; Chen, Jin-Quan; Yang, Xing-Xing; Hao, Er-Jun; Dong, Zhi-Bing published an article in European Journal of Organic Chemistry. The title of the article was 《Synthesis of Diaryl Sulfides by Using Tetramethylthiuram Monosulfide (TMTM) as Organosulfur Source: A Practical C(sp2)-S Bond Construction》.SDS of cas: 589-87-7 The author mentioned the following in the article:
A protocol for synthesizing sym. thioethers RSR (R = Ph, 4-ethoxyphenyl, thiophen-2-yl, etc.) by using a cheap organosulfur reagent (tetramethylthiuram monosulfide: TMTM) was developed. Both iodobenzenes RI and phenylboronic acids RB(OH)2 react well with TMTM, giving the target products with good to excellent yields. This method features simple performance, wide functional group tolerance, and good to excellent yields, showing a potential application value for the synthesis of drug mols. In addition to this study using 1-Bromo-4-iodobenzene, there are many other studies that have used 1-Bromo-4-iodobenzene(cas: 589-87-7SDS of cas: 589-87-7) was used in this study.
1-Bromo-4-iodobenzene(cas: 589-87-7) has been employed as reagent for in situ desilylation and coupling of silylated alkynes, as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids), as substrate in copper-free Sonogashira coupling in aqueous acetone in synthesis of β,β,dibromostyrenesSDS of cas: 589-87-7
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com