《Asymmetric Three-Component Heck Arylation/Amination of Nonconjugated Cyclodienes》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Zhu, Daoyong; Jiao, Zhiwei; Chi, Yonggui Robin; Goncalves, Theo P.; Huang, Kuo-Wei; Zhou, Jianrong Steve. Product Details of 15164-44-0 The article mentions the following:
Substituted cyclohexylamines are becoming increasingly important in drug discovery. Asym. Heck insertion/amination of nonconjugated cyclodienes proceeds to give 5-aryl cyclohexenylamines with good enantioselectivity and exclusive trans configurations. Primary and secondary anilines, indoline, and benzylamines are suitable amines. The weakly donating diphosphite Kelliphite forms a deep unsym. pocket, which is essential for stereoselective anti attack of amines. In the experiment, the researchers used many compounds, for example, 4-Iodobenzaldehyde(cas: 15164-44-0Product Details of 15164-44-0)
4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Product Details of 15164-44-0
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com