《Photochemical Functionalization of Heterocycles with EBX Reagents: C-H Alkynylation versus Deconstructive Ring Cleavage》 was published in Chemistry – A European Journal in 2020. These research results belong to Voutyritsa, Errika; Garreau, Marion; Kokotou, Maroula G.; Triandafillidi, Ierasia; Waser, Jerome; Kokotos, Christoforos G.. COA of Formula: C7H5IO2 The article mentions the following:
Herein, a cheap and efficient photochem. method for the C-H functionalization of saturated O-heterocycles, as well as the deconstructive ring-cleavage of S-heterocycles, employing hypervalent iodine alkynylation reagents (ethynylbenziodoxolones, EBX) were reported. This photochem. alkynylation was performed utilizing phenylglyoxylic acid as the photoinitiator, leading to the corresponding products in good to high yields, under household fluorescent light bulb irradiation When O-heterocycles were employed, the expected α-C-H alkynylation took place. In contrast, oxidative ring-opening to form a thioalkyne and an aldehyde was observed with S-heterocycles. Preliminary mechanistic experiments were presented to give first insights into this puzzling divergent reactivity. In the experiment, the researchers used 2-Iodobenzoic acid(cas: 88-67-5COA of Formula: C7H5IO2)
2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. COA of Formula: C7H5IO2 Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com