The author of 《Palladium-catalyzed regioselective C2-arylation of 5-aminoindole》 were Taskesenligil, Yunus; Lafzi, Ferruh; Kilic, Haydar; Saracoglu, Nurullah. And the article was published in Journal of Heterocyclic Chemistry in 2019. Synthetic Route of C6H4BrI The author mentioned the following in the article:
Pd(II)-catalyzed C-H arylations of 5-aminoindole using iodobenzenes as aryl source was studied. Despite pivalamide directing group at 5-position of the indole, the direct C2-arylation of the indole observed in high yields and with high regioselectivity.1-Bromo-4-iodobenzene(cas: 589-87-7Synthetic Route of C6H4BrI) was used in this study.
1-Bromo-4-iodobenzene(cas: 589-87-7) is mainly used as the OLED pharmaceutical intermediate, as reagent for in situ desilylation and coupling of silylated alkynes, as substrate in copper-free Sonogashira coupling in aqueous acetone..Synthetic Route of C6H4BrI It is also used in synthesis of β,β,dibromostyrenes, as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids)
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com