Recommanded Product: 83410-16-6On October 25, 1982 ,《Studies on pyrimidine derivatives. XXX. The palladium-catalyzed cross-coupling reactions of iodopyrimidines with terminal olefinic compounds》 was published in Chemical & Pharmaceutical Bulletin. The article was written by Sakamoto, Takao; Arakida, Hiroko; Edo, Kiyoto; Yamanaka, Hiroshi. The article contains the following contents:
The influence of Ph3P, used as a ligand, on the palladium-catalyzed cross-coupling reactions of iodopyrimidines with olefins such as H2C:CHCO2Et, H2C:CHCN, H2C:CHPh was investigated. The effect of Ph3P in the monoazine series is also discussed. Thus, coupling of 2-iodo-4,6-dimethylpyrimidine with N2C:CHCO2Et in presence of Pd(OAc)2 gave 57% pyrimidine I. Using Pd(OAc)2-2Ph3P as a catalyst gave no I.4-Chloro-5-iodo-2,6-dimethylpyrimidine(cas: 83410-16-6Recommanded Product: 83410-16-6) was used in this study.
4-Chloro-5-iodo-2,6-dimethylpyrimidine(cas: 83410-16-6) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Recommanded Product: 83410-16-6
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com