In 2019,Asian Journal of Organic Chemistry included an article by Padmavathi, Rayavarapu; Babu, Srinivasarao Arulananda. Synthetic Route of C7H7I. The article was titled 《Palladium-Catalyzed 8-Aminoquinoline-Aided sp2 δ-C-H Intramolecular Amidation/Annulation: A Route to Tricyclic Quinolones》. The information in the text is summarized as follows:
Systematic investigations of a Pd(II)-catalyzed, 8-aminoquinoline directing group (DG)-aided sp2 δ-C-H amidation (C-N bond formation) of different biaryl carboxamides were reported. Various biaryl carboxamides with suitably positioned sp2 δ-C-H bond with respect to the DG were assembled via β-C-H arylation and then they were subjected to Pd(II)-catalyzed sp2 δ-C-H intramol. amidation/annulation reactions. While the intramol. amidation of the sp2 δ-C-H bond of some carboxamides was not fruitful, several biaryl carboxamides underwent intramol. amidation of their sp2 δ-C-H bonds to afford various tricyclic quinolone motifs such as, phenanthridin-6(5H)-ones and thieno-/furo-/pyrrolo-[2,3-c]quinolin-4(5H)-ones. The assembly of the required biaryl carboxamides possessing the sp2 δ-C-H bond via the β-C-H arylation and the successive intramol. amidation (C-N bond formation) of the resulting biaryl carboxamides were also performed in one-pot reaction conditions to afford tricyclic quinolones. In addition to this study using 1-Iodo-4-methylbenzene, there are many other studies that have used 1-Iodo-4-methylbenzene(cas: 624-31-7Synthetic Route of C7H7I) was used in this study.
1-Iodo-4-methylbenzene(cas: 624-31-7) undergoes Suzuki-Miyaura coupling reaction with phenylboronic acid catalyzed by (Ni,Mg)3Si2O5(OH)4 solid-solution nanotubes loaded with palladium.Synthetic Route of C7H7I
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com