In 2022,Jia, Shiqi; Tian, Yuhong; Li, Xin; Wang, Pengfei; Lan, Yu; Yan, Hailong published an article in Angewandte Chemie, International Edition. The title of the article was 《Atroposelective Construction of Nine-Membered Carbonate-Bridged Biaryls》.Recommanded Product: 4-Chloro-2-iodoaniline The author mentioned the following in the article:
The authors herein demonstrate an efficient method for the atroposelective construction of nine-membered carbonate-bridged biaryls, e.g., I, through vinylidene ortho-quinone methide (VQM) intermediates. Diverse products with desirable pharmacol. features were synthesized in satisfying yields and good to excellent enantioselectivities. In subsequent bioassays, several agents showed considerable antiproliferative activity via the mitochondrial-related apoptosis mechanism. Further transformations produced more structural diversity and may inspire new ideas for developing functional mols. The experimental part of the paper was very detailed, including the reaction process of 4-Chloro-2-iodoaniline(cas: 63069-48-7Recommanded Product: 4-Chloro-2-iodoaniline)
4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.Recommanded Product: 4-Chloro-2-iodoaniline
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com