Gao, Qianwen; Wu, Chenggui; Deng, Shuang; Li, Lisha; Liu, Ze-Shui; Hua, Yu; Ye, Jinxiang; Liu, Chang; Cheng, Hong-Gang; Cong, Hengjiang; Jiao, Yinchun; Zhou, Qianghui published their research in Journal of the American Chemical Society in 2021. The article was titled 《Catalytic Synthesis of Atropisomeric o-Terphenyls with 1,2-Diaxes via Axial-to-Axial Diastereoinduction》.Recommanded Product: 1-Iodonaphthalene The article contains the following contents:
A modular and convergent strategy for the assembly of atropisomeric o-terphenyls with 1,2-diaxes via palladium/chiral norbornene cooperative catalysis and axial-to-axial diastereoinduction was reported. Readily available aryl iodides, 2,6-substituted aryl bromides and potassium aryl trifluoroborates were used as the building blocks, laying the foundation for diversity-oriented synthesis of these scaffolds (46 examples). Other features included the unique axial-to-axial diastereoinduction mode, construction of two axes in a single operation and step economy. DFT calculations were performed to rationalize the axial-to-axial diastereoinduction process. Synthetic utilities of this method in preparation of atropisomeric oligophenyls, chiral catalysts and ligands were demonstrated. In the experiment, the researchers used 1-Iodonaphthalene(cas: 90-14-2Recommanded Product: 1-Iodonaphthalene)
1-Iodonaphthalene(cas: 90-14-2) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Recommanded Product: 1-Iodonaphthalene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com