Fash, David M.’s team published research in Bioorganic & Medicinal Chemistry Letters in 2016 | CAS: 624-73-7

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Quality Control of 1,2-Diiodoethane

In 2016,Fash, David M.; Peer, Cody J.; Li, Zhenwu; Talisman, Ian J.; Hayavi, Sima; Sulzmaier, Florian J.; Ramos, Joe W.; Sourbier, Carole; Neckers, Leonard; Figg, W. Douglas; Beutler, John A.; Chain, William J. published 《Synthesis of a stable and orally bioavailable englerin analogue》.Bioorganic & Medicinal Chemistry Letters published the findings.Quality Control of 1,2-Diiodoethane The information in the text is summarized as follows:

Synthesis of analogs of englerin A with a reduced propensity for hydrolysis of the glycolate moiety led to a compound (I) which possessed the renal cancer cell selectivity of the parent and was orally bioavailable in mice.1,2-Diiodoethane(cas: 624-73-7Quality Control of 1,2-Diiodoethane) was used in this study.

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Quality Control of 1,2-Diiodoethane

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com