《Spatial Anion Control on Palladium for Mild C-H Arylation of Arenes》 was published in Journal of the American Chemical Society in 2020. These research results belong to Dhankhar, Jyoti; Gonzalez-Fernandez, Elisa; Dong, Chao-Chen; Mukhopadhyay, Tufan K.; Linden, Anthony; Coric, Ilija. SDS of cas: 625-99-0 The article mentions the following:
C-H arylation of arenes without the use of directing groups is a challenge, even for simple mols., such as benzene. We describe spatial anion control as a concept for the design of catalytic sites for C-H bond activation, thereby enabling nondirected C-H arylation of arenes at ambient temperature The mild conditions enable late-stage structural diversification of biol. relevant small mols., and site-selectivity complementary to that obtained with other methods of arene functionalization can be achieved. These results reveal the potential of spatial anion control in transition-metal catalysis for the functionalization of C-H bonds under mild conditions. In the experiment, the researchers used many compounds, for example, 1-Chloro-3-iodobenzene(cas: 625-99-0SDS of cas: 625-99-0)
1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides.SDS of cas: 625-99-0 The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com