In 2019,Angewandte Chemie, International Edition included an article by Clare, Daniel; Dobson, Benjamin C.; Inglesby, Phillip A.; Aissa, Christophe. HPLC of Formula: 1774-47-6. The article was titled 《Chemospecific Cyclizations of α-Carbonyl Sulfoxonium Ylides on Aryls and Heteroaryls》. The information in the text is summarized as follows:
The functionalization of aryl and heteroaryls using α-carbonyl sulfoxonium ylides without the help of a directing group has remained so far a neglected area, despite the advantageous safety profile of sulfoxonium ylides (safety: an α-diazo ketone was potentially explosive, whereas an α-carbonyl sulfoxonium ylide was not). Described herein are the cyclizations of α-carbonyl sulfoxonium ylides onto benzenes, benzofurans and N-p-toluenesulfonyl indoles in the presence of a base in HFIP [e.g., I → II (91%) in presence of K2CO3 in HFIP], whereas pyrroles and N-Me indoles undergo cyclization in the presence of an iridium catalyst. Significantly, these two sets of conditions are chemospecific for each groups of substrates. In addition to this study using Trimethylsulfoxonium iodide, there are many other studies that have used Trimethylsulfoxonium iodide(cas: 1774-47-6HPLC of Formula: 1774-47-6) was used in this study.
Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.HPLC of Formula: 1774-47-6
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com