SDS of cas: 619-58-9In 2021 ,《A Strategy for Site- and Chemoselective C-H Alkenylation through Osmaelectrooxidative Catalysis》 appeared in Angewandte Chemie, International Edition. The author of the article were Choi, Isaac; Messinis, Antonis M.; Hou, Xiaoyan; Ackermann, Lutz. The article conveys some information:
Osmaelectrocatalyzed C-H activations that set the stage for electrooxidative alkynes e.g., 1-methoxy-4-[2-(4-methoxyphenyl)ethynyl]benzene annulations by benzoic acids e.g., 2-methylbenzoic acid were described. The osmium electrocatalysis enables site- and chemoselective electrooxidative C-H activations with unique levels of selectivity. The isolation of unprecedented osmium(0) I and osmium(II) intermediates [OsCl2(p-cymene)]2, along with crystallog. characterization and analyses by spectrometric and spectroscopic in operando techniques delineate a synergistic osmium redox catalyst regime. Detailed mechanistic studies revealed a facile C-H cleavage, which allows for an ample substrate scope, providing provide robust and user-friendly access to annulated heterocycles II. In the experiment, the researchers used 4-Iodobenzoic acid(cas: 619-58-9SDS of cas: 619-58-9)
4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. SDS of cas: 619-58-9 Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com