In 2022,Chang, Fengwei; Wang, Chengyi; Chen, Qipeng; Zhang, Yongjin; Liu, Guohua published an article in Angewandte Chemie, International Edition. The title of the article was 《A Chemoenzymatic Cascade Combining a Hydration Catalyst with an Amine Dehydrogenase: Synthesis of Chiral Amines》.Category: iodides-buliding-blocks The author mentioned the following in the article:
An encapsulated Au/carbene combined with a free amine dehydrogenase as a co-catalyst system that enabled an efficient hydration/amination enantioselective cascade process to be accomplished was developed. The mechanistic investigation disclosed dual catalysis comprised of alkyne hydration, followed by a reductive amination process. In the experimental materials used by the author, we found 3-Iodophenol(cas: 626-02-8Category: iodides-buliding-blocks)
3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the SimmonsSmith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Category: iodides-buliding-blocks
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com