In 2015,Organic & Biomolecular Chemistry included an article by Camacho-Garcia, J.; Montoro-Garcia, C.; Lopez-Perez, A. M.; Bilbao, N.; Romero-Perez, S.; Gonzalez-Rodriguez, D.. Synthetic Route of C4H4IN3O. The article was titled 《Synthesis and complementary self-association of novel lipophilic π-conjugated nucleoside oligomers》. The information in the text is summarized as follows:
A series of lipophilic nucleosides comprising natural and non-natural bases that are π-conjugated to a short oligo-phenylene-ethynylene fragment has been synthesized. These bases comprise guanosine, isoguanosine, and 2-amino-adenosine as purine heterocycles, and cytidine, iso-cytosine and uridine as complementary pyrimidine bases. The hydrogen-bonding dimerization and association processes between complementary bases were also studied by 1H NMR and absorption spectroscopy in order to obtain the relevant association constants2-Amino-5-iodopyrimidin-4(1H)-one(cas: 3993-79-1Synthetic Route of C4H4IN3O) was used in this study.
2-Amino-5-iodopyrimidin-4(1H)-one(cas: 3993-79-1) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.Synthetic Route of C4H4IN3O
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com