《Copper promoted desulfurization and C-N cross coupling reactions: Simple approach to the synthesis of substituted 2-aminobenzoxazoles and 2,5-disubstituted tetrazole amines》 was written by Boddapati, S. N. Murthy; Saketi, Jagan Mohana Rao; Mutchu, Baby Ramana; Bollikolla, Hari Babu; Adil, Syed Farooq; Khan, Mujeeb. Recommanded Product: 625-99-0 And the article was included in Arabian Journal of Chemistry in 2020. The article conveys some information:
Copper-catalyzed novel, facile and efficient methods for the synthesis of various 2-aminobenzoxazoles and 2,5-diphenyltetrazoleamines was demonstrated. The reaction procedures were simple, with excellent substrate tolerance in good to high yields thus paving an excellent and useful way to establish a library of potentially active drug mols. This methodol. represents the first concept of copper-catalyst promoted domino C-N cross-coupling reaction towards the construction of 2-aminobenzoxazoles. In addition, the synthesis of 2,5-diaryltetrazoleamines using copper via inter mol. C-N cross-coupling reaction with aryl iodides was also reported. The proposed reaction mechanism involves copper based desulfurization/nucleophilic substitution and subsequent C-N cross-coupling reactions. Numerous applications of this methodol. was established for synthesizing diverse heterocyclic derivatives i.e. both electron rich and electron deficient systems. The experimental part of the paper was very detailed, including the reaction process of 1-Chloro-3-iodobenzene(cas: 625-99-0Recommanded Product: 625-99-0)
1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Recommanded Product: 625-99-0
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com